For treating restless legs syndrome (RLS), the dosage of Horizant is typically 600 mg a day. For postherpetic neuralgia, the standard dosage is 600 mg twice a day. It should be noted that taking a higher dose does not increase the medication's effectiveness, but it does increase the risk of side effects.
The dosage for Horizant™ (gabapentin enacarbil) that your healthcare provider recommends will vary, depending on the condition being treated and how well your kidneys are functioning. As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.
The standard dosing for restless legs syndrome (RLS) treatment is 600 mg once daily, with food, at approximately 5 p.m. Higher doses have been shown to increase the risk of side effects without providing any additional benefit.
For people taking the recommended dose (600 mg once daily), this medication can be stopped abruptly if necessary. For people taking more than the recommended dose, the medication should be stopped gradually.
People with kidney disease may need to be on a lower dosage, such as 300 mg once a day or every other day, depending on how poorly their kidneys are functioning.
The standard dosing for postherpetic neuralgia treatment is 600 mg twice daily, with food. Usually, 600 mg once a day for the first three days is recommended (before going to twice a day) to help minimize side effects.
Higher doses have been shown to increase the risk of side effects without providing any additional benefit.
People with kidney disease may need to be on a lower dosage, such as 600 mg once a day, 300 mg once a day, or even 300 mg every other day, depending on how poorly their kidneys are functioning.
Do not stop taking this medication abruptly, as this increases the risk for seizures. Usually, your healthcare provider will recommend reducing your dosage to once a day for a week before you stop it altogether.